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MSM은 글루타치온 농도를 80% 증량한다.

MSM Raises Glutathione by 80%
MSM Raises Glutathione by 80%
Date:   2/8/2009 8:42:15 AM   ( 5 y ) ... viewed 7943 times
this is a very simple study. they gave mice MSM in their drinking water then checker their glutathione levels. they discovered that simple oral intake of MSM raised glutathione levels by 80%. not bad.

http://www.fasebj.org/cgi/content/meeting_abstract/22/1_MeetingAbstracts/445.8


Methylsulfonylmethane (MSM) Intake in Mice Produces Elevated Liver Glutathione and Partially Protects Against Carbon Tetrachloride-Induced Liver Injury

Robert A DiSilvestro, David J DiSilvestro and Daniel J DiSilvestro

Human Nutrition, The Ohio State University, Columbus, OH

ABSTRACT

Methylsulfonylmethane (MSM) is a organic molecule present in small amounts in a number of foods and sold as a dietary supplement. MSM’s antioxidant actions have been proposed based mostly on indirect evidence. For example, antioxidant actions in vivo of a related compound, DMSO, may be produced by MSM formed in vivo from DMSO. Thus, a study was done in mice to determine whether oral intake of MSM (OptiMSM®, Bergstrom Nutrition) could affect tissue levels of an internal sulfur-containing antioxidant, glutathione, and resistance to chemically-induced oxidant stress.

MSM administration (5 weeks, 80 mg/100 ml drinking water) produced a statistically significant increase in liver glutathione (mean increase of 78%). A similar effect was not seen in lung or skeletal muscle.

In addition, MSM partially inhibited liver injury after injection of carbon tetrachloride, which induces liver oxidant stress (injury evaluation based on blood indexes of hepatic injury). These results indicate the need for further testing for MSM antioxidant actions in vivo, and to explore the mechanism of elevated glutathione. This work was supported in part by an unrestricted research gift from Bergstrom Nutrition.

Dr. 무연(이영철) 14-03-25 11:37
 
쥐 실험에서  물100cc에 80mg의 MSM을 5주간 주었더니, 간에서 글루타티온이 78%이 증가되어 간의 손상을 막아준다는 논문입니다.
아트레유 14-03-25 12:41
 
굉장하네요. 쥐에게 물100cc MSM80mg이면 사람을 기준으로 몇cc 몇g정도인가요?
Dr. 무연(이영철) 14-03-25 14:16
 
인체는 하루에 필요한 물( maintemance fluid )이 150cc 기준 물컵으로 8잔 ~ 12잔 , 1.2L ~ 1.8L 로 환산하구요.
MSM은 질병 상태에 따라 2g ~ 8g 예측합니다.
아트레유 14-03-25 21:51
 
사람에게 일반적으로 권장되는 용량정도로 주어졌네요. 상당히 인상적입니다.

http://d046.kkk24.kr/bbs/board.php?bo_table=sub09_2&wr_id=13
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